Effect of Use of Different Anthelmintics (Piperazine Citrate and Ivermectine) on Blood Profile of Infested Poultry (Commercial and Rural Layers)

This research was conducted to describe the therapeutic effect of ivermectin and piperazine citrate on blood profile in commercial layer birds and rural poultry. Two experiments named 1 and 2 were performed representing commercial layer birds and rural poultry respectively. Each experiment was consisted of 4 groups of 15 birds each named A, B, C, D, (Experiment No 1) and W, X, Y and Z (Experiment No 2). To make the birds parasitic free, Albendazole @14mg /Kg were administered in all birds. In subgroups A, B, C, W, X and Y Ascaridia galli infection was inoculated orally @ dose rate of 2500 embryonated eggs per bird using crop tube. To confirm infestation 5 birds were euthanized from each treatment group at day 28 of post infection. Ivermectin @ dose rate of 200μg/kg was given in birds of treatment groups A and W, and Piperazine citrate @ dose rate of 32 mg/100 kg in birds of treatment groups C and Z. At day 10 (post treatment) six birds from each group were blood sampled to check blood profile. Blood analysis showed same (P > 0.05) effect of both anthelmintics on serum cholesterol, serum T3, serum creatinine, serum cortisol level, ESR and respiratory rate of infested birds whilst Piperazine citrate administration showed higher (P < 0.05) serum T4 level, and lower (P < 0.05) serum urea level in infested birds.